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Home / Store / Wellness / Metagenics / Metagenics Axis Endo (formerly Estrium)

Metagenics Axis Endo (formerly Estrium)

Specialized Support for Hormone Metabolism in Men and Women


Axis Endo™ is a phytonutrient nutrition powder designed for men and women to help support healthy estrogen and testosterone metabolism and to help support bone, cardiovascular, and neurological function.*

Axis Endo features key vitamins, minerals, and phytochemicals that influence pathways of estrogen and testosterone metabolism and may help reduce oxidative stress in sensitive tissues.* This multidimensional formula features flaxseed lignans, calcium D-glucarate and zinc.

Serving size: 2 Scoops (39 g)
Servings Per Container: 14

Ingredients     Amount Per Serving     % Daily Value

  • Calories     130      
  • Total Fat     4 g     5%*
  • Total Carbohydrate     14 g     5%*
  •    Dietary Fiber     7 g     28%*
  •    Sugars     2 g    
  • Protein     13 g    
  • Vitamin A (as mixed carotenoids)     750 mcg     83%
  • Vitamin C (as ascorbic acid)     60 mg     67%
  • Vitamin D (as cholecalciferol)     25 mcg (1,000 IU)     125%
  • Vitamin E (as d-alpha tocopheryl succinate)     201 mg     1,340%
  • Vitamin K (as menaquinone and phylloquinone)     75 mcg     63%
  • Thiamin (as thiamin HCl)     0.75 mg     63%
  • Riboflavin     1 mg     77%
  • Niacin (as niacinamide)     12 mg     75%
  • Vitamin B6 (as pyridoxine HCl)     50 mg     2,941%
  • Folate (as calcium L-5-methyltetrahydrofolate)†     680 mcg DFE     170%
  • Vitamin B12 (as methylcobalamin)     300 mcg     12,500%
  • Biotin     150 mcg     500%
  • Pantothenic Acid (as calcium D-pantothenate)     5 mg     100%
  • Calcium (as calcium D-glucarate and calcium citrate)     500 mg     38%
  • Iron (as ferrous fumarate)     8 mg     44%
  • Phosphorous     350 mg     28%
  • Iodine (as potassium iodide)     100 mcg     67%
  • Magnesium (as magnesium citrate)     200 mg     48%
  • Zinc (as zinc citrate)     12 mg     109%
  • Manganese (as manganese sulfate)     1 mg     43%
  • Chromium (as chromium picolinate)     100 mcg     286%
  • Sodium     120 mg     5%
  • Potassium (as dipotassium phosphate and potassium iodide)     400 mg     9%
  • Calcium D-Glucarate     1.5 g     **
  • Milk Thistle (Silybum marianum) Seed Extract providing 140 mg silymarin†† (containing silybin, isosilybin, silydianin, silychristin)     280 mg     **
  • Proprietary Mix of Curcumin [from Curcuma longa L. rhizome extract standardized to 40% (40 mg) curcuminoids] and Fenugreek Galactomannans (from Trigonella foenum-graecum seed extract)     100 mg     **
  • N-Acetyl-L-Cysteine     100 mg     **
  • Rosemary (Rosmarinus officinalis) Leaf Extract (standardized to 7.6% min sum of carnosol+carnosic acid)     100 mg     **
  • Dried Melon (Cucumis melo L.) Pulp Juice Concentrate [standardized to 140 IU superoxide dismutase (SOD)]     10 mg     **
  • Mixed Carotenoids (including beta-carotene, alpha-carotene, cryptoxanthin, zeaxanthin, and lutein)     1.5 mg     **
  • Menaquinone-7 (MK-7)     15 mcg     **
Other Ingredients:
Pea protein isolate, rice protein concentrate, apple fiber, partially hydrolyzed guar gum, high oleic sunflower oil, medium-chain triglycerides, natural flavors,^ tapioca flour, silica, mono and diglycerides, Luo Han Guo fruit (monk fruit) extract, and hydrogenated palm oil.^^

Blend or shake 2 level scoops (39 grams) of Axis Endo into 8 fluid ounces of water, juice, or soy, almond, rice, coconut or organic cow’s milk once or twice daily as directed by your healthcare practitioner. For highly sensitive individuals, consider reducing consumption to 1/2 to 1 scoop with 4-5 ounces of chilled water or recommended fluid twice daily during the first 3-4 days before starting a full daily dose.

This product is non-GMO and gluten-free.

Do not use if pregnant or nursing. Consult your healthcare practitioner prior to use if taking medications or other nutritional supplements. Keep out of the reach of children.

Tamper Evident: Do not use if package is torn or open.

Storage: Keep closed in a cool, dry place.

*Percent Daily Values are based on a 2,000 calorie diet.
**Daily Value not established.

††As Metafolin®. Metafolin® is a registered trademark of Merck KGaA, Darmstadt Germany
††By HPLC analysis
^^RSPO certified (Roundtable on Sustainable Palm Oil)

WARNING: Consuming this product can expose you to chemicals including lead, which are known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to

Please type in the coupon HealthyMe when you check out to get a 10% discount on your Metagenics order.

International orders - shipping is greater than the amount on your receipt.

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Dietary Information
Dietary Considerations:
  • Wheat Free
  • Dairy/Mile Free
  • Gluten Free
  • Vegetarian
  • Soy Free
  • Preservative Free
  • Shellfish Free

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